Comparison Mercedes-Benz S-class Long (W221) S 450 (340 Hp) 4MATIC G-TRONIC & Mercedes-Benz ML (W166) AMG ML 63 (523 Hp) 4MATIC SPEEDSHIFT G-TRONIC
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| Brand: | Mercedes-Benz | Mercedes-Benz |
| Model: | S-class | M-class |
| Generation: | S-class Long (W221) | ML (W166) |
| Engine / modification: | S 450 (340 Hp) 4MATIC G-TRONIC | AMG ML 63 (523 Hp) 4MATIC SPEEDSHIFT G-TRONIC |
| Production start: | 2006 year | 2012 year |
| Production end: | 2009 year | 2015 year |
| Coupe type: | Sedan | SUV |
| Num. of Doors: | 4 | 5 |
| Num. of seats: | 5 | 5 |
| Fuel consumption / economy - urban: | 17-17.2 l/100 km | 15.7 l/100 km |
| Fuel consumption / economy - extra urban: | 8.6-8.8 l/100 km | 9.6 l/100 km |
| Fuel consumption / economy - combined: | 11.7-11.9 l/100 km | 11.8 l/100 km |
| Fuel Type: | Petrol (Gasoline) | Petrol (Gasoline) |
| Fuel tank volume: | 90 l | 93 l |
| Emission standard: | Euro 5 | |
| CO2 emissions: | 279-284 g/km | 276 g/km |
| Power: | 340 hp | 523 hp |
| Max power in: | 6000 rpm. | 5250-5750 rpm. |
| Maximum speed: | 250 km/h | 250 km/h |
| Acceleration from 0 to 100 km/h: | 5.9 sec | 4.8 sec |
| Torque: | 460 Nm @ 2700-5000 rpm. | 700 Nm @ 1750-5000 rpm. |
| Engine position: | Front, longitudinal | Front, longitudinal |
| Engine displacement: | 4663 cm3 | 5461 cm3 |
| Fuel System: | Multi-point injection | Direct injection |
| Aspiration / Turbine: | Twin-Turbo | |
| Position of cylinders: | V engine | V engine |
| Number of cylinders: | 8 | 8 |
| Number of valves per cylinder: | 4 | |
| Compression ratio: | 10.5 | 10 |
| Piston Stroke: | 86 mm | |
| Cylinder Bore: | 92.9 mm | |
| Wheel Drive: | All wheel drive (4x4) | All wheel drive (4x4) |
| Number of Gears (automatic transmission): | 7G-TRONIC | AMG SPEEDSHIFT PLUS 7G-TRONIC |
| Length: | 5209 mm | 4804 mm |
| Width: | 1872 mm | 1926 mm |
| Width including mirrors: | 2115 mm | |
| Height: | 1473 mm | 1796 mm |
| Wheelbase: | 3165 mm | 2915 mm |
| Front track: | 1604 mm | 1648 mm |
| Rear (Back) track: | 1606 mm | 1663 mm |
| Front overhang: | 871 mm | |
| Rear overhang: | 1173 mm | |
| Minimum volume of Luggage (trunk): | 690 l | |
| Maximum amount of Luggage (trunk): | 560 l | 2010 l |
| Front suspension: | Pneumatic elastic element | Double wishbone |
| Rear suspension: | Pneumatic elastic element | Multi-link independent |
| Max weight: | 2640 kg | 3050 kg |
| Front brakes: | Ventilated discs | Ventilated discs |
| Rear brakes: | Ventilated discs | Ventilated discs |
| Kerb Weight: | 1980 kg | 2345 kg |
| ABS: | yes | yes |
| Steering type: | Steering rack and pinion | Steering rack and pinion |
| Power steering: | Electric Steering | |
| Minimum turning circle (turning diameter): | 12.2 m | 11.8 m |
| Tire size: | 235/55 R17 | 265/45 R20 |
| Wheel rims size: | R17 | R20 |