Comparison Mercedes-Benz S-class Long (W221, facelift 2009) S 500 BlueEFFICIENCY V8 (435 Hp) G-TRONIC & Mercedes-Benz E-class (W212) E 350 CGI (292 HP) 7G-Tronic
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| Brand: | Mercedes-Benz | Mercedes-Benz |
| Model: | S-class | E-class |
| Generation: | S-class Long (W221, facelift 2009) | E-class (W212) |
| Engine / modification: | S 500 BlueEFFICIENCY V8 (435 Hp) G-TRONIC | E 350 CGI (292 HP) 7G-Tronic |
| Production start: | 2011 year | 2009 year |
| Production end: | 2013 year | 2013 year |
| Coupe type: | Sedan | Sedan |
| Num. of Doors: | 4 | 4 |
| Num. of seats: | 5 | 5 |
| Fuel consumption / economy - urban: | 12.9-13.4 l/100 km | 12.5 l/100 km |
| Fuel consumption / economy - extra urban: | 7.3-7.4 l/100 km | 6.6 l/100 km |
| Fuel consumption / economy - combined: | 9.4-9.6 l/100 km | 8.8 l/100 km |
| Fuel Type: | Petrol (Gasoline) | Petrol (Gasoline) |
| Fuel tank volume: | 83 l | 80 l |
| Emission standard: | EURO V | EURO V |
| CO2 emissions: | 219-224 g/km | |
| Power: | 435 hp | 292 hp |
| Max power in: | 5250 rpm. | 6400 rpm. |
| Maximum speed: | 250 km/h | 250 km/h |
| Acceleration from 0 to 100 km/h: | 5 sec | 6.3 sec |
| Torque: | 700 Nm @ 1800-3500 rpm. | 365 Nm |
| Engine position: | Front, longitudinal | Front, longitudinal |
| Engine displacement: | 4663 cm3 | 3498 cm3 |
| Fuel System: | Direct injection | Direct injection |
| Aspiration / Turbine: | Twin-Turbo | |
| Position of cylinders: | V engine | V engine |
| Number of cylinders: | 8 | 6 |
| Number of valves per cylinder: | 4 | 4 |
| Compression ratio: | 10.5 | 12.2 |
| Piston Stroke: | 86 mm | |
| Cylinder Bore: | 92.8 mm | |
| Wheel Drive: | Rear wheel drive | Rear wheel drive |
| Number of Gears (automatic transmission): | 7G-TRONIC | 7 |
| Length: | 5226 mm | 4868 mm |
| Width: | 1871 mm | 1854 mm |
| Width including mirrors: | 2120 mm | |
| Height: | 1479 mm | 1471 mm |
| Wheelbase: | 3165 mm | 2874 mm |
| Front track: | 1600 mm | 1585 mm |
| Rear (Back) track: | 1606 mm | 1604 mm |
| Front overhang: | 888 mm | |
| Rear overhang: | 1173 mm | |
| Minimum volume of Luggage (trunk): | 560 l | |
| Maximum amount of Luggage (trunk): | 540 l | |
| Front suspension: | Multi-link suspension | |
| Rear suspension: | Multi-link independent | |
| Max weight: | 2655 kg | 2280 kg |
| Front brakes: | Disc | Ventilated discs |
| Rear brakes: | Disc | Disc |
| Kerb Weight: | 2000 kg | 1735 kg |
| ABS: | yes | yes |
| Steering type: | Steering rack and pinion | Steering rack and pinion |
| Minimum turning circle (turning diameter): | 12.2 m | 11.25 m |
| Tire size: | 255/45 R18 | 205/60 R 16 W |
| Wheel rims size: | R18 |